Anidiabetic drugs (except for insulin) are for the most part pharmacological specialists that have been endorsed for hyperglycemic treatment in type 2 diabetes mellitus (DM). On the off chance that way of life adjustments (weight reduction, dietary alteration, and exercise) don't adequately lessen A1C levels (target level: ∼ 7%), pharmacological treatment with antidiabetic medications ought to be started. These medications might be arranged by their system of activity as insulinotropic or non-insulinotropic. They are accessible as monotherapy or mix treatments, with the last including two (or, less regularly, three) antidiabetic drugs as well as insulin. The specific treatment calculations are investigated in the treatment segment of diabetes mellitus. The medication of decision for all kind 2 diabetic patients is metformin. This medication effectsly affects glucose digestion and advances weight reduction or if nothing else weight adjustment. What's more difficulties, various investigations have shown that metformin can decrease mortality and the danger of difficulties. On the off chance that metformin is contraindicated, not endured, or doesn't adequately control blood glucose levels, another class of antidiabetic medication might be directed. Most antidiabetic drugs are not suggested or ought to be utilized with alert in patients with moderate or serious renal disappointment or other critical comorbidities. Oral antidiabetic drugs are not suggested during pregnancy or breastfeeding.