Ankle arthritis is a result of damaged or worn cartilage at the joint that connects the foot to the leg. It may be the result of injury, wear and tear, deformity or inflammation. In the early stages, activity modification, weight loss, rest and acetaminophen are the primary treatment strategies. As the arthritis progresses, bracing and physical therapy may be needed. Surgery can be successful in treating ankle arthritis when it does not respond to non-surgical management.