Angiosarcoma Scientific Journals
Angiosarcoma could be a rare, aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis related to a generally poor prognosis, unless diagnosed early. Given the vascular endothelial cell origin of angiosarcoma, tumours may develop in essentially any organ; however, there's a predilection for the skin where half all tumours arise, increasing in prevalence with age. the foremost common risk factors are chronic lymphoedema and history of radiation. We review the foremost important radiological findings along the spectrum of angiosarcoma from head to toe throughout the body, including uncommon and rare locations. Key imaging features of angiosarcoma across multiple organ systems are described, similarly because the impact on management and prognosis. Angiosarcoma is an aggressive, malignant endothelial-cell tumour of lymphatic or vascular origin.1–3 it's a high rate of local recurrence and metastasis. Angiosarcoma represents <1% of all soft-tissue sarcomas, with a generally poor prognosis and overall survival ranging anywhere from 6 to 16 months. Angiosarcoma arises from vascular endothelial cells which show atypia and may grow along pre-existing vascular channels, sinusoidal or cavernous spaces. they'll also form poorly organized vessels, solid masses or nodules.8 The pathological appearance of angiosarcoma varies in step with the tumour grade. Low-grade angiosarcoma displays alittle solid component with low-grade cytology and abundant open vascular lumina. High-grade lesions are densely cellular and infiltrative with a high mitotic rate and atypical cells. High-grade tumours have a variable amount of vascular lumen formation which will be focal in appearance.
Last Updated on: Nov 23, 2024