Angioplasty or Percutaneous coronary intervention involves non-surgical widening of the arteria, employing a balloon catheter to dilate the artery from within. A metallic stent is sometimes placed within the artery after dilatation. Antiplatelet agents also are used. Stents is also either bare metal or drug-eluting. this system for treating multiple conditions, including unstable angina, acute infarction and multi-vessel arteria disease. Scholarly referee is that the process of subjecting an author's scholarly work, research, or ideas to the scrutiny of others who are experts within the same field, before a paper describing this work is published during a journal. The work is also accepted, considered acceptable with revisions, or rejected. referee requires a community of experts during a given (narrowly defined) field, who are qualified and ready to perform reasonably impartial review. Whether adding percutaneous transluminal angioplasty and stenting (PTAS) to background medical treatment is effective for decreasing the incidence of stroke or death in patients with symptomatic intracranial atherosclerosis (ICAS) remains controversial. We perform a randomised controlled trial to look at the effectiveness and safety of an improved PTAS procedure for patients with ICAS. A randomised controlled trial are going to be conducted in three hospitals in China. Eligible patients with ICAS are going to be randomly assigned to receive medication treatment (MT) plus PTAS or MT alone. The MT are going to be initiated immediately after randomisation, while the PTAS are going to be performed when patients report relief of alarm symptoms defined as sudden weakness or numbness. All patients are going to be followed up at 30 days, 3 and 12 months after randomisation. the first end point are going to be the incidence of stroke or death at 30 days after randomisation.