Used by more than 1,500 hospitals and over 35,000 retail pharmacies in the U.S., as well as government and managed care agencies, PBMs, pharmaceutical manufacturers and academic institutions, Clinical Pharmacology sets the standard for today’s referential and point-of-care drug information solutions. Clinical Pharmacology is accepted by all 50 state Boards of Pharmacy as a compendium to fulfill the drug reference requirements for licensed pharmacies, and is officially recognized by the Centres for Medicare and Medicaid Services (CMS) as a drug compendium for determining the appropriate use of drugs and biologics for cancer patients. Proven by multiple independent research studies, Clinical Pharmacology is the most complete, easiest-to-use and most dependable drug information solution available today is underpinned by the basic science of pharmacology, with added focus on the application of pharmacological principles and methods in the real world. It has a broad scope, from the discovery of new target molecules, to the effects of drug usage in whole populations. Clinical pharmacologists are physicians, pharmacists, and scientists whose focus is developing and understanding new drug therapies. Clinical pharmacologists work in a variety of settings in academia, industry and government. In the laboratory setting they study biomarkers, pharmacokinetics, drug metabolism and genetics. In the office setting they design and evaluate clinical trials, create and implement regulation guidelines for drug use, and look at drug utilization on local and global scales. In the clinical setting they work directly with patients, participate in experimental studies, and investigate adverse reactions and interactions.  Clinical Pharmacology, in theory, has been practiced for centuries through observing the effects of herbal remedies and early drugs on humans. Most of this work was done through trial and error. In the early 1900s, scientific advances allowed scientists to combine the study of physiological effects with biological effects. This led to the first major breakthrough when scientists used clinical pharmacology to discover insulin. Since that discovery clinical pharmacology has expanded to be a multidisciplinary field and has contributed to the understanding of drug interaction, therapeutic efficacy and safety in humans. Over time clinical pharmacologists have been able to make more exact measurements and personalize drug therapies. The information can be published in our peer reviewed journal with impact factors and are calculated using citations not only from research articles but also review articles (which tend to receive more citations), editorials, letters, meeting abstracts, short communications, and case reports. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and try to increase their number rapidly. Impact factor plays a major role for the particular journal. Journal with higher impact factor is considered to be more important than other ones.