Chandrayee Ghosh, PhD
Research Scientist, surgery
Stanford, Stanford, United States
Biography
I have a broad background in the field of Cancer and Immunology, with specific training and expertise in cancer therapeutics and translational science pertaining to natural compounds and drug repurposing. Currently I work in the department of Surgery at Stanford , extensively on patient sample.My current research includes identifying novel functions of FDA approved compounds and their combinations in targeting endocrine cancers and assessing their mechanism of actions. I have worked elaborately in pancreatic ductal adenocarcinoma and have identified the potential interaction KDM3A with DCLK-1 and their role in PDAC tumorigenesis and stemness. In this work I also established that N-oxalylglycine (NOG), ?-ketoglutarate mimetic affects KDM3A activity. In another project I focused on identifying the cluster of master transcription factors or Super-Enhancers as novel targets for Pancreatic Adenocarcinoma using Combination of natural Compounds as anticancer agents. My doctoral thesis was on identification and characterization of Toll-like Receptors (TLR-2, 4, 6) in thymic, splenic and lymph node lymphocytes and macrophages of Swiss albino mice and their role in S. aureus infection and lipopolysaccharide administration. In addition, I have successfully published my research works in good peer-reviewed journals.
Research Interest
Translational science, clinical samples, surgical patient sample, cancer research
